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VectorBuilder GmbH ets1 overexpression cmv vectors
(A-D) Scatter plots showing correlation between ETS1 expression and the hEMT score in (A) human HNSCC scRNA-seq cohort, (B) UASCC cell lines, (C) TCGA HNSCC tumors, (D) HNSCC PDO samples. (E) Stacked plot illustrating ETS1 ChIP-Seq peaks on hEMT genes from two cell lines. (F) A Venn diagram showing shared ETS1 ChIP-Seq peaks between the KYSE150 and SCC25 cell lines, with representative peaks shown in (G). (H-K) GSEA line plots showing enrichment of the hEMT gene signature following ETS1 <t>overexpression</t> (H) or knockdown (I), or in ETS1-high tumors within TCGA ESCC (J) and HNSCC (K) cohorts. (L) An IGV plot showing H3K27ac ChIP-Seq profiles in nonmalignant esophageal tissues, primary ESCC, and lymph node (LN) metastases (PRJNA665151), with quantification shown in panel (M). (N) ETS1 mRNA expression in the same samples as panel (L) and in GSE9349 (P) dataset. (O) Motif sequence enrichment analysis of gained H3K27ac peaks in LN metastases from PRJNA665151.
Ets1 Overexpression Cmv Vectors, supplied by VectorBuilder GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ets1 overexpression cmv vectors/product/VectorBuilder GmbH
Average 90 stars, based on 1 article reviews
ets1 overexpression cmv vectors - by Bioz Stars, 2026-02
90/100 stars

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1) Product Images from "ETS1 Orchestrates a Hybrid EMT Program Driving in vivo Metastasis and Immune Evasion"

Article Title: ETS1 Orchestrates a Hybrid EMT Program Driving in vivo Metastasis and Immune Evasion

Journal: bioRxiv

doi: 10.1101/2025.07.17.665404

(A-D) Scatter plots showing correlation between ETS1 expression and the hEMT score in (A) human HNSCC scRNA-seq cohort, (B) UASCC cell lines, (C) TCGA HNSCC tumors, (D) HNSCC PDO samples. (E) Stacked plot illustrating ETS1 ChIP-Seq peaks on hEMT genes from two cell lines. (F) A Venn diagram showing shared ETS1 ChIP-Seq peaks between the KYSE150 and SCC25 cell lines, with representative peaks shown in (G). (H-K) GSEA line plots showing enrichment of the hEMT gene signature following ETS1 overexpression (H) or knockdown (I), or in ETS1-high tumors within TCGA ESCC (J) and HNSCC (K) cohorts. (L) An IGV plot showing H3K27ac ChIP-Seq profiles in nonmalignant esophageal tissues, primary ESCC, and lymph node (LN) metastases (PRJNA665151), with quantification shown in panel (M). (N) ETS1 mRNA expression in the same samples as panel (L) and in GSE9349 (P) dataset. (O) Motif sequence enrichment analysis of gained H3K27ac peaks in LN metastases from PRJNA665151.
Figure Legend Snippet: (A-D) Scatter plots showing correlation between ETS1 expression and the hEMT score in (A) human HNSCC scRNA-seq cohort, (B) UASCC cell lines, (C) TCGA HNSCC tumors, (D) HNSCC PDO samples. (E) Stacked plot illustrating ETS1 ChIP-Seq peaks on hEMT genes from two cell lines. (F) A Venn diagram showing shared ETS1 ChIP-Seq peaks between the KYSE150 and SCC25 cell lines, with representative peaks shown in (G). (H-K) GSEA line plots showing enrichment of the hEMT gene signature following ETS1 overexpression (H) or knockdown (I), or in ETS1-high tumors within TCGA ESCC (J) and HNSCC (K) cohorts. (L) An IGV plot showing H3K27ac ChIP-Seq profiles in nonmalignant esophageal tissues, primary ESCC, and lymph node (LN) metastases (PRJNA665151), with quantification shown in panel (M). (N) ETS1 mRNA expression in the same samples as panel (L) and in GSE9349 (P) dataset. (O) Motif sequence enrichment analysis of gained H3K27ac peaks in LN metastases from PRJNA665151.

Techniques Used: Expressing, ChIP-sequencing, Over Expression, Knockdown, Sequencing



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VectorBuilder GmbH ets1 overexpression cmv vectors
(A-D) Scatter plots showing correlation between ETS1 expression and the hEMT score in (A) human HNSCC scRNA-seq cohort, (B) UASCC cell lines, (C) TCGA HNSCC tumors, (D) HNSCC PDO samples. (E) Stacked plot illustrating ETS1 ChIP-Seq peaks on hEMT genes from two cell lines. (F) A Venn diagram showing shared ETS1 ChIP-Seq peaks between the KYSE150 and SCC25 cell lines, with representative peaks shown in (G). (H-K) GSEA line plots showing enrichment of the hEMT gene signature following ETS1 <t>overexpression</t> (H) or knockdown (I), or in ETS1-high tumors within TCGA ESCC (J) and HNSCC (K) cohorts. (L) An IGV plot showing H3K27ac ChIP-Seq profiles in nonmalignant esophageal tissues, primary ESCC, and lymph node (LN) metastases (PRJNA665151), with quantification shown in panel (M). (N) ETS1 mRNA expression in the same samples as panel (L) and in GSE9349 (P) dataset. (O) Motif sequence enrichment analysis of gained H3K27ac peaks in LN metastases from PRJNA665151.
Ets1 Overexpression Cmv Vectors, supplied by VectorBuilder GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ets1 overexpression cmv vectors/product/VectorBuilder GmbH
Average 90 stars, based on 1 article reviews
ets1 overexpression cmv vectors - by Bioz Stars, 2026-02
90/100 stars
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(A-D) Scatter plots showing correlation between ETS1 expression and the hEMT score in (A) human HNSCC scRNA-seq cohort, (B) UASCC cell lines, (C) TCGA HNSCC tumors, (D) HNSCC PDO samples. (E) Stacked plot illustrating ETS1 ChIP-Seq peaks on hEMT genes from two cell lines. (F) A Venn diagram showing shared ETS1 ChIP-Seq peaks between the KYSE150 and SCC25 cell lines, with representative peaks shown in (G). (H-K) GSEA line plots showing enrichment of the hEMT gene signature following ETS1 overexpression (H) or knockdown (I), or in ETS1-high tumors within TCGA ESCC (J) and HNSCC (K) cohorts. (L) An IGV plot showing H3K27ac ChIP-Seq profiles in nonmalignant esophageal tissues, primary ESCC, and lymph node (LN) metastases (PRJNA665151), with quantification shown in panel (M). (N) ETS1 mRNA expression in the same samples as panel (L) and in GSE9349 (P) dataset. (O) Motif sequence enrichment analysis of gained H3K27ac peaks in LN metastases from PRJNA665151.

Journal: bioRxiv

Article Title: ETS1 Orchestrates a Hybrid EMT Program Driving in vivo Metastasis and Immune Evasion

doi: 10.1101/2025.07.17.665404

Figure Lengend Snippet: (A-D) Scatter plots showing correlation between ETS1 expression and the hEMT score in (A) human HNSCC scRNA-seq cohort, (B) UASCC cell lines, (C) TCGA HNSCC tumors, (D) HNSCC PDO samples. (E) Stacked plot illustrating ETS1 ChIP-Seq peaks on hEMT genes from two cell lines. (F) A Venn diagram showing shared ETS1 ChIP-Seq peaks between the KYSE150 and SCC25 cell lines, with representative peaks shown in (G). (H-K) GSEA line plots showing enrichment of the hEMT gene signature following ETS1 overexpression (H) or knockdown (I), or in ETS1-high tumors within TCGA ESCC (J) and HNSCC (K) cohorts. (L) An IGV plot showing H3K27ac ChIP-Seq profiles in nonmalignant esophageal tissues, primary ESCC, and lymph node (LN) metastases (PRJNA665151), with quantification shown in panel (M). (N) ETS1 mRNA expression in the same samples as panel (L) and in GSE9349 (P) dataset. (O) Motif sequence enrichment analysis of gained H3K27ac peaks in LN metastases from PRJNA665151.

Article Snippet: For overexpression cloning, ETS1 overexpression CMV vectors were purchased from the Vectorbuilder. pLenti CMV V5-LUC Blast vector was from Addgene (#21474).

Techniques: Expressing, ChIP-sequencing, Over Expression, Knockdown, Sequencing