ets1 overexpression cmv vectors (VectorBuilder GmbH)
Structured Review

Ets1 Overexpression Cmv Vectors, supplied by VectorBuilder GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ets1 overexpression cmv vectors/product/VectorBuilder GmbH
Average 90 stars, based on 1 article reviews
Images
1) Product Images from "ETS1 Orchestrates a Hybrid EMT Program Driving in vivo Metastasis and Immune Evasion"
Article Title: ETS1 Orchestrates a Hybrid EMT Program Driving in vivo Metastasis and Immune Evasion
Journal: bioRxiv
doi: 10.1101/2025.07.17.665404
Figure Legend Snippet: (A-D) Scatter plots showing correlation between ETS1 expression and the hEMT score in (A) human HNSCC scRNA-seq cohort, (B) UASCC cell lines, (C) TCGA HNSCC tumors, (D) HNSCC PDO samples. (E) Stacked plot illustrating ETS1 ChIP-Seq peaks on hEMT genes from two cell lines. (F) A Venn diagram showing shared ETS1 ChIP-Seq peaks between the KYSE150 and SCC25 cell lines, with representative peaks shown in (G). (H-K) GSEA line plots showing enrichment of the hEMT gene signature following ETS1 overexpression (H) or knockdown (I), or in ETS1-high tumors within TCGA ESCC (J) and HNSCC (K) cohorts. (L) An IGV plot showing H3K27ac ChIP-Seq profiles in nonmalignant esophageal tissues, primary ESCC, and lymph node (LN) metastases (PRJNA665151), with quantification shown in panel (M). (N) ETS1 mRNA expression in the same samples as panel (L) and in GSE9349 (P) dataset. (O) Motif sequence enrichment analysis of gained H3K27ac peaks in LN metastases from PRJNA665151.
Techniques Used: Expressing, ChIP-sequencing, Over Expression, Knockdown, Sequencing